PUBLICATIONS
Shaku MT, Ocius KL, Apostolos AJ, Pires MM, VanNieuwenhze MS, Dhar N, Kana BD. "Amidation of glutamate residues in mycobacterial peptidoglycan is essential for cell wall cross-linking." (2023) Front Cell Infect Microbiol, 13:1205829.
Liu Z, Lepori I, Chordia MD, Dalesandro BE, Guo T, Dong J, Siegrist MS, Pires MM. "A Metabolic-Tag-Based Method for Assessing the Permeation of Small Molecules Across the Mycomembrane in Live Mycobacteria." (2023) Angew Chem Int Ed Engl. 62, e202217777.
Immunotargeting of Gram-Positive Pathogens via a Cell Wall Binding Tick Antifreeze Protein.
Dalesandro BE, Pires MM. J Med Chem. 2023 Jan 12;66(1):503-515.
Ongwae GM, Lepori I, Chordia MD, Dalesandro BE, Apostolos AJ, Siegrist MS, Pires M. "Measurement of Small Molecule Accumulation into Diderm Bacteria." (2023), ACS Infectious Diseases, 9, 970110.
Apostolos AJ, Chordia MD, Kolli SH, Dalesandro BE, Rutkowski MR, Pires M. "Real-time non-invasive fluorescence imaging of gut commensal bacteria to detect dynamic changes in the microbiome of live mice." (2022), Cell Chemical Biology, S2451.
Apostolos AJ, Kelly J, Ongwae G., Pires M."Structure Activity Relationship of the Murein Peptide in Sortase A mediated Ligation from Staphylococcus aureus" (2022), ChemBioChem, 23, e20220412.
Ferraro NJ, Pires M. "Genetic Determinants of Surface Accessibility in Staphylococcus aureus" (2022), Bioconjugate Chemistry, 33, 767-772.
Apostolos AJ, Yehiya TK, Silva JR, Lameira J, Alves MC, Siegrist MS, Pires M. "Metabolic Processing of Selenium-based Bioisostere of meso-diaminopimelic Acid in Live Bacteria" (2022), Biochemistry, 61, 1404-1414.
Ongwae G, Chordia M, Cawley JL, Dalesandro BE, Wittenberg NJ, Pires M. "Targeting of Pseudomonas aeruginosa Cell Surface via GP12, an Escherichia coli Specific Bacteriophage" Scientific Reports (2021), 12, 721.
Apostolos AJ, Pires M. "Impact of Crossbridge Structure on Peptidoglycan Crosslinking: A Synthetic Stem Peptide Approach" Methods in Enzymology (2022), 625, 259-279.
Sikorski EL, Wehr J, Ferraro NJ, Pires M, Thévenin D. "Selective Display of a Chemoattractant Agonist on Cancer Cells Activates the Formyl Peptide Receptor 1 on Immune Cells" ChemBioChem (2021), 23, e202100521.
Ferraro NJ, Kim S, Im W, Pires M. "Systematic Assessment of Accessibility to the Surface of Staphylococcus aureus." ACS Chemical Biology (2021) 16, 2527-2536.
Dalesandro BE, Pires M. "Induction of Endogenous Antibody Recruitment to the Surface of the Pathogen Enterococcus faecium." ACS Infectious Diseases (2021) 14, 1116-1125.
Apostolos AJ, Ferraro NJ, Dalesandro BE, Pires M. "SaccuFlow: A High-Throughput Analysis Platform to Investigate Bacterial Cell Wall Interactions." ACS Infectious Diseases (2021) 7, 2483-2491.
Wehr J, Sikorski EL, Bloch E, Feigman MS, Ferraro NJ, Baybutt TR, Snook AE, Pires M, Thévenin D. "pH-Dependent Grafting of Cancer Cells with Antigenic Epitopes Promotes Selective Antibody-Mediated Cytotoxicity. Journal of Medicinal Chemistry (2020), 63, 3713-3722.
Dalesandro BE, Pires M. “Induction of Induction of Endogenous Antibody Recruitment to the Surface of the Pathogen Enterococcus faecium.” ACS Infectious Diseases (2020), 7, 1116-1125.
Apostolos AJ, Nelson J, Pires M. “Facile Synthesis and Metabolic Incorporation of m-DAP Bioisosteres Into Cell Walls of Live Bacteria.” ACS Chemical Biology (2020), 15, 2966-2975.
Apostolos AJ, Pidgeon SE, Pires M. “Remodeling of Cross-bridges Controls Peptidoglycan Cross-linking Levels in Bacterial Cell Walls.” ACS Chemical Biology (2020), 15,1261-1267.
Ongwae GM, Morrison KR, Allen RA, Kim S, Im W, Wuest WM, Pires M. “Broadening Activity of Polymyxin by Quaternary Ammonium Grafting.” ACS Infectious Diseases (2020) 6, 1427-1435.
Wehr J, Sikorski EL, Bloch E, Feigman MS, Ferraro NJ, Baybutt TR, Snook AE, Pires M, Thévenin D. “pH-Dependent Grafting of Cancer Cells With Antigenic Epitopes Promotes Selective Antibody-Mediated Cytotoxicity.” Journal of Medicinal Chemistry (2020) 63, 3713-3722.
Wang L, Jakob S, Wang H, Apostolos A, Pires M, Xu XG. “Generalized Heterodyne Configurations for Photoinduced Force Microscopy.” Analytical Chemistry (2019) 91, 13251-13259.
Pidgeon S, Apostolos A, Nelson J, Shaku M, Rimal B, Islam M, Crick C, Kim J, Pavelka S, Kana D, Pires M. “L,D-Transpeptidase Specific Probe Reveals Spatial Activity of Peptidoglycan Cross-Linking.” ACS Chemical Biology (2019) 14, 2185-2196.
Kim S, Pires M, Im W. “Insight into Elongation Stages of Peptidoglycan Processing in Bacterial Cytoplasmic Membranes.” Scientific Reports (2018) 8, 17704.
Sabulski M, Yu Y, Pidgeon S, Ongwae G, Regen S, Im W, Pires M. “Synthetic Immunotherapeutics Against Gram-negative Pathogens.” Cell Chemical Biology (2018) 225, 1185-1194.
Feigman M, Pires M. “Synthetic Immunobiotics: A Future Success Story in Small Molecule-Based Immunotherapy?” ACS Infectious Diseases (2018) 4, 664-672.
Sabulski M, Pidgeon S, Pires M. “Immuno-Targeting of Staphylococcus aureus via Surface Remodeling Complexes.” Chemical Science (2017) 8, 6804-6809.
Pidgeon S, Pires M. “Cell Wall Remodeling of Staphylococcus aureus in Live Hosts.” Bioconjugate Chemistry (2017) 28, 2310-2315.
Pidgeon S, Pires M. “Vancomycin-dependent Response in Live Drug-Resistant Bacteria via Metabolic Labeling.” Angewandte Chemie Int Engl. (2017) 12, 8839-8843.
Pidgeon S, Pires M. “Cell Wall Remodeling by a Synthetic Analog Reveals Metabolic Adaptation in Vancomycin Resistant Enterococci.” ACS Chemical Biology (2017) 12, 1913-1918.
Fura J, Sarkar S, Pidgeon S, Pires M. “Combatting Bacterial Pathogens with Immunomodulation and Infection Tolerance Strategies.” Current Topics in Medicinal Chemistry (2017) 17, 290-304.
Yu Y, Sabulski M, Schell W, Pires M, Perfect J, Regen S. “Simple Strategy for Taming Membrane-Disrupting Antibiotics.” Bioconjugate Chemistry (2016) 27, 2850-2853.
Fura J, Pidgeon S, Birabaharan M, Pires M. “Dipeptide-Based Metabolic Labeling of Bacterial Cells for Endogenous Antibody Recruitment.” ACS Infections Diseases (2016), 2, 302-309.
Sarkar S, Libby E, Pidgeon S, Dworkin J, Pires M. “In Vivo Probe of Lipid II-Interacting Proteins.” Angewandte Chemie Int Engl. (2016), 55, 8401-8404.
Sabulski M, Wang Y, Pires M. “PAD2 Activity Monitored via a Fluorescent Substrate Analog.” Chemical Biology & Drug Design (2015) 4, 599-605.
Fura J, Kearns D, Pires M. “D-Amino Acid Probes for Penicillin Binding Protein-based Bacterial Surface Labeling.” Journal of Biological Chemistry (2015) 51, 30540-30550.
Fura J, Pires M. “D-amino carboxamide-based recruitment of dinitrophenol antibodies to bacterial surfaces via peptidoglycan remodeling.” Biopolymers (2015) 4, 351-359.
Pidgeon S, Pires M. “Metabolic remodeling of bacterial surfaces via tetrazine ligations.” Chemical Communications (2015) 51, 10330-10333.
Pidgeon S, Fura J, Leon W, Birabaharan M, Vezenov D, Pires M. “Metabolic Profiling of Bacteria by Unnatural C-terminated D-Amino Acids.” Angewandte Chemie Int Engl. (2015) 21, 6158-6162.
Sarkar S, Pires M. “D-Amino acids do not inhibit biofilm formation in Staphylococcus aureus.” PLoS One (2015) 2, e0117613.
Sabulski M, Fura J, Pires M. “Fluorescence-Based Monitoring of PAD4 Activity via a Pro-fluorescence Substrate Analog.” Journal of Visualized Experiments (2014) 93, e52114.
Fura J, Sabulski M, Pires M. “D-Amino Acid Mediated Recruitment of Endogenous Antibodies to Bacterial Surfaces.” ACS Chemical Biology (2014) 9, 1480-1489.
Wildeman E, Pires M. “Facile Fluorescence-Based Detection of PAD4-Mediated Citrullination.” ChemBioChem (2013) 14, 963-967.
Hrycyna CA, Summers RL, Lehane AM, Pires M, Namanja H, Bohn K, Kuriakose J, Ferdig M, Henrich PP, Fidock DA, Kirk K, Chmielewski J, Martin RE. “Quinine Dimers Are Potent Inhibitors of the Plasmodium Falciparum Chloroquine Resistance Transporter and Are Active Against Quinoline-Resistant P. Falciparum.” ACS Chemical Biology (2014) 21, 722-730.
Reig A, Pires M, Synder RA, Wu Y, Jo H, Kulp D, Calhoun J, Szyperski T, Solomon E, DeGrado W. “Altering the O2-Dependent Reactivity of de novo Due Ferri Proteins.” Nature Chemistry (2012) 11, 900-906.
Pires M, Lee JY, Ernenwein D, Chmielewski J. “Controlling the Morphology of Metal-Promoted Higher Ordered Assemblies of Collagen Peptides with Varied Core Lengths.” Langmuir (2012) 28, 1993-1997.
Pires M, Przybyla D, Rubert Perez CM, Chmielewski J. “Metal-mediated Tandem Co-assembly of Collagen Peptides into Banded Microstructures.” Journal of the American Chemical Society (2011) 137, 14469-14471.
Pires M, Ernenwein D, Chmielewski J. “Selective Decoration and Release of His-tagged Proteins from Metal-Assembled Collagen Peptide Microflorettes.” Biomacromolecules (2011) 7, 2429-2433.
Namaja H, Emmert D, Pires M, Hrycyna C, Chmielewski J. “Inhibition of P-glycoprotein Transport and Binding Using a Galantamine Dimer.” Biochemical and Biophysical Research Communications (2009) 388, 672-676.
Pires M, Przybyla D, Chmielewski J. “Metal Collagen Framework for 3-D Cell Culture.” Angewandte Chemie Int Engl. (2009) 48, 7813-7817.
Pires M, Chmielewski J. “Self-Assembly of Collagen Peptides into Microflorettes via Metal Coordination.” Journal of the American Chemical Society (2009) 131, 2706-2712.
Pires M, Emmert D, Hrycyna C, Chmielewski J. “Inhibition of P-Glycoprotein-Mediated Taxol Resistance by Reversibly-Linked Quinine Homodimers.” Molecular Pharmacology (2009) 75, 92-100.
Pires M, Chmielewski J. “Fluorescence Imaging of Cellular Glutathione using Latent Rhodamine.” Organic Letters (2008) 10, 837-840.
Pires M, DeTuri, V. “Structural, Energetic, and Infrared Spectra Insights into Methanol Clusters (CH3OH)n, for n = 2-12, 16, 20. ONIOM as an Efficient Method of Modeling Large Methanol Clusters.” Journal of Chemical Theory and Computation (2007) 3, 1073-1082.
Pires M, Hrycyna C, Chmielewski J. “Bivalent Probes of the Multidrug Transporter P-glycoprotein.” Biochemistry (2006) 45, 11695-11702.